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Can virus-based defective interfering particles (DIPS) be used to treat dengue infection?

Infection by dengue virus causes incapacitating and potentially dangerous acute disease in humans. Dengue is a mosquito-borne infectious disease with about 100 million serious clinical infections annually. Considerable effort in drug development is underway, but no effective drug therapy is available. A major difficulty for drug development is the rapid evolution of RNA viruses, like dengue virus, which presents a major challenge for controlling virus transmission and infection using conventional pharmaceuticals and vaccines.This project is based on the observation that …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

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